Senegal's President Macky Sall said that 11 newborn babies died in a fire at the neonatal section of a regional hospital in the town of Tivaouane.
He said the blaze broke out in the hospital's neonatal unit on Wednesday.
"I have just learned with pain and consternation the death of 11 newborn babies in the fire that occurred in the neonatology department of the Mame Abdou Aziz Sy Dabakh hospital in Tivaouane," Sall said in a tweet without giving further details about the fire.
"To their mothers and their families, I express my deepest sympathy," Sall, who is on a state visit in Angola, added.
Health minister, Abdoulaye Diouf Sarr, said on private Senegalese television TFM that "according to preliminary investigation, a short circuit triggered the fire".
Sarr, who is in Geneva for the World Health Assembly, said he would cut short the trip and return to Senegal immediately.
Tivaouane, one of Senegal's holy cities and a transport hub, is located around 120 km east of the capital Dakar.