Hundreds of protesters battled police in the heart of Barcelona amid anger over the jailing of Catalan separatist leaders.
Masked protestors were seen blocking areas, damaging police vehicles, setting fire to large garbage bins, ransacking banks and attacking riot police officers with stones, cans and bottles.
Police responded with repeated volleys of foam bullets, smoke grenades, tear gas and water cannons.
The violence followed a largely peaceful demonstration that drew more than half a million people onto the streets of the Catalan capital.
Catalan interior affairs chief Miquel Buch distanced themselves from the riots, claiming "this kind of violence is unprecedented in Catalonia ... these people are not separatists".
Some 128 people have been arrested in the region over the past five days, with Spain's acting interior minister, Fernando Grande-Marlaska, warning that rioters faced up to six years in prison.
The US State Department said on Friday it has approved a sale worth $151.8 million to Israel for munitions and munitions support, without submitting it for congressional review.
Flash floods across Nairobi overnight has left at least 23 people dead, authorities said, adding that dozens of cars were swept away and flights at East Africa's biggest airport disrupted.
Russia launched a barrage of drones and missiles at Ukraine overnight on Saturday, damaging infrastructure and killing at least 10 people in the northeast city of Kharkiv, Ukrainian officials said.
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