A Boeing 767 cargo jetliner crashed into a bay outside of Houston airport with three people on board.
Atlas Air Flight 3591, which was was en route to Houston from Miami, lost radar and radio contact about 48 km southeast of the airport.
Eyewitnesses reported that the plane, which was operating for Amazon, crashed nose-first into the bay.
Authorities told media that they did not believe there were any survivors.
In a Facebook post, the Chambers County Sheriff's office said the plane had been located in Jack's Pocket, and an official investigation launched into the incident.

Thailand's Queen Mother Sirikit dies at 93
Louvre transfers jewels to Bank of France after heist
Russian aerial attack on Kyiv kills two, injures 13, Ukraine officials say
Thai PM to sign Cambodia ceasefire deal, cuts short ASEAN trip after royal death
UK seizes record haul of illegal weight-loss drugs in factory raid
