Novak Djokovic begins his Australian Open title defence against Jeremy Chardy after the draw for the year's first Grand Slam was made on Friday.
World number one Djokovic captured a record-extending eighth title at Melbourne Park last year by beating Dominic Thiem, who is seeded third and faces Mikhail Kukushkin.
Rafael Nadal, seeking a first title at the major since 2009, faces Laslo Djere in his opener.
Reigning women's champion Sofia Kenin will meet wildcard Maddison Inglis.
Top-ranked Ash Barty resumes her quest to become the first homegrown singles winner at the Australian Open since 1978 when the 24-year-old takes on Danka Kovinic.
American Serena Williams, looking to win a record-equalling 24th Grand Slam, meets Laura Siegemund in the opening round while 2019 champion Naomi Osaka faces Anastasia Pavlyuchenkova.
Chelsea's Maresca fumes over 'stupid, embarrassing' Delap red card
Liverpool thrashed by Palace, holders Newcastle through in League Cup
Vacherot beats cousin Rinderknech at Masters again in Paris
South Africa humble England to reach ICC Women's World Cup final
First Australia-India Twenty20 washed out by Canberra rain
