The World Health Organisation has said it has lost communication with its contacts in Al Shifa hospital in northern Gaza.
In a statement it expressed its deep concern about the safety of health workers and hundreds of sick and injured people, including children in nurseries and displaced persons, who remain inside.
The hospital is the largest medical complex in Gaza.
According to the latest reports, the number of in-patients is almost double the hospital's capacity, although services are limited to emergency care needed to save lives.
The organisation reiterated its call for an immediate ceasefire in Gaza "as the only way to save lives and put an end to the horrific suffering there".
North China building fire kills 14
Trump to meet Qatar's prime minister as Iran diplomacy faces hurdles
Trump says he is unlikely to order Iran attack if talks progress
Train collision in Egypt’s Giza province kills 7, injures dozens
Saudi coalition says two Houthi missile launchers destroyed in Saada
