Todd Phillips' 'Joker' won the Golden Lion award at the Venice Film Festival.
Joker, starring Joaquin Phoenix, had received an eight-minute standing ovation at its premiere in the Italian city on Saturday.
"I want to thank Warner Bros and DC for stepping out of their comfort zone and taking such a bold swing on me and this movie," director Todd Phillips said in his acceptance speech.
"There is no movie without Joaquin Phoenix ... Joaquin is the fiercest and bravest and most open-minded lion that I know."
The movie follows superhero Batman's nemesis' transformation from vulnerable loner to confident villain.
Meanwhile, Roman Polanski's military drama An Officer and a Spy took the Silver Lion Grand Jury Prize.
Italian actor Luca Marinelli won best actor for Martin Eden, while France's Ariane Ascaride won best actress for Gloria Mundi.
Best director went to Sweden's Roy Andersson About Endlessness, while Italian director Franco Maresca won the Special Jury Prize for satirical documentary Mafia Is No Longer What It Used to Be.
Best screenplay went to Chinese filmmaker Yonfan for the animation No. 7 Cherry Lane.
The child star of the "Baby Shark Dance" video, the most-watched video in YouTube history, has released his first K-pop digital single on Thursday, a decade after he first found fame.
American actress Hayden Panettiere, famed for roles in television shows such as 'Nashville' and 'Heroes', has died aged 36, her family said in a statement issued by her publicist on Sunday.
Attorneys for Nick Reiner on Monday have urged a judge to allow him to use his $1.5 million trust fund to pay for his defense against charges that he killed his parents, Hollywood director Rob Reiner and producer-photographer Michele Reiner.
A former street gang leader orchestrated the 1996 drive-by shooting of hip-hop star Tupac Shakur in Las Vegas in retribution for the beating of his nephew, a prosecutor told jurors during opening statements in a murder trial tied to a long-unsolved crime that became a seminal moment in rap history.
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