Newcastle United dumped Manchester City out of the League Cup 1-0 on Wednesday and drew a fourth round trip to holders Manchester United, who beat them in last season's final, as their reward.
Swedish forward Alexander Isak broke the deadlock in the second half at St James' Park after a much-changed City dominated possession in the first 45 minutes but failed to take their chances.
Newcastle soaked up the pressure and were transformed after the break, with Isak slotting in at the back post off a low cross from Joelinton in the 53rd.
City had Phil Foden and regular goal machine Erling Haaland on the bench while Newcastle started only goalkeeper Nick Pope from the team that won 8-0 at Sheffield United in the league last Sunday.
Manchester United beat Crystal Palace, also their league opponents next weekend, 3-0 at Old Trafford on Tuesday.
High-flying Brighton & Hove Albion also went out on Wednesday, beaten 1-0 at Chelsea, while Aston Villa and Brentford both lost at home to their top flight opponents Everton (2-1) and Arsenal (1-0) respectively.
Everton's reward was a home match against Burnley, manager Sean Dyche's previous club.
Record nine times winners Liverpool beat Leicester City 3-1 at Anfield after a side stripped of their familiar stars went a goal down to the second-tier leaders with just three minutes gone.
The win was Liverpool's seventh in a row in all competitions and the 2022 winners will travel to Premier League rivals Bournemouth, 2-0 winners at Championship side Stoke City thanks to two second-half goals in three minutes, for the fourth round.
Fulham won 2-1 at home against second-tier Norwich City, with Nigeria midfielder Alex Iwobi scoring on his first start for the Londoners, and will have another trip east in the next round against Ipswich Town.
West Ham United won 1-0 at League One Lincoln City and host Arsenal next.
The Gunners had England international Aaron Ramsdale back in goal after former Brentford keeper David Raya had started the previous three games.
Reiss Nelson scored what turned out to be the winner after eight minutes at the Community Stadium.
Blackburn Rovers thrashed Championship rivals Cardiff City 5-2 in the highest-scoring match of the night and are at Chelsea next.
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